The homogenization step was carried out with the maximum value of melt overheating not exceeding 50 K.
In process optimization, maximum values of melting latent heat were achieved as 148.5 J/g.
It was expected, that the values of melting temperature decrease, bending angles and KD values clearly define the row of model DNA substrate properties such as Flu-dU-DNA >> nAnt ≈ Fap-dC-DNA.
Although FT MTB is a qualitative assay, signal values of melting curve peaks can be read from the corresponding graphs.
During the second heating scan, the melting temperatures (Tm) were noted as the maximum value of the melting peaks, whereas the glass-transition temperature (T g ) was determined using the midpoint temperature of the glass transition.
The values of T peak, T onset for DTG and HF curves, the mass loss percentage (Δm) and the heat of fusion value (ΔH f ) of melting event of procaine and benzocaine respectively, in various excipient mixtures, are presented in Table 2.
The melting temperature (Tm) was noted as the maximum value of the melting peaks, and the glass transition temperature (Tg) was determined from the midpoint temperature of the glass transition.
However, insertion of regioisomerism defects inside crystals influences more the value of the melting point of the α form than for the β crystal.
Pareek and Bhamniya (2013) used the Taguchi and ANOVA methods for finding an optimum value of the melting temperature, injection pressure and cooling time for an injection molding process.
