Exact(1)
Also, the predicted value of each run was determined.
Similar(58)
Then the statistical results will be displayed in the figures and tables on the GUI, and the corresponding experimental result (i.e., final population and its performance indicator values) of each run will be saved to a.mat file.
Then we repeatedly fit the parameters to the dataset, except for p43 which is fixed with a different value for each run of the fitting.
We performed 10 independent long runs (106 burn-in steps, 107 total steps) for each value of K (1≤K≤6), for a total of 60 runs (Table S2), and assessed convergence through the observation of the ALPHA value for each run.
To obtain the empirical distributions of the eight elementary test statistics and the novel combined statistic, one thousand calculations for each method were run in which case neutral was assumed in the corresponding populations, and the maximum observed value of each test statistic in each run was stored.
The running time of ScanIndel and Pindel is measured as the sum of running times for each chromosome and the peak memory is the maximum value of each individual run.
Numerical values of each separate run were normalized against the Non-Target Control to generate the graphs.
GSA of the model of ER-dependent gene expression was performed according to the following algorithm: We perturbed all independent kinetic parameters of the model (dissociation and reaction rate constants) and total concentrations of model species, with the exception of the inhibitor concentration (It), whose value was fixed to a certain value during each run of GSA.
The program records the input values and output values at the end of each run and then repeats the process.
Table 3 Key GA behavioral parameters values applied to four runs and the optimal objective function value found after 2000 iterations Run 1 Run 2 Run 3 Run 4 P m 0.8 0.5 0.2 Variable P c 0.2 0.5 0.8 Optimal solution found TMD (m) 2352 2352 2354 2352 The optimal objective function value for each iteration of each run is illustrated as trends in Fig. 6 (Case 1).
If average values of control samples of each run were not within 3% of the true value, the run was repeated.
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