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(iii) Thermal cycling over a four month duration revealed that the value of binding capacity changed depending on the exposure temperature.
The attached DHBP groups gave a large value of binding constant K for the complexation with adenosine having a pair of cis-OH groups, whereas the K values for the DHBP groups with adenosine phosphates were extremely small.
Both UV Vis and steady state fluorescence measurements reveal large value of binding constant (K) for C70 1 system (∼6.94 × 104 dm3 mol−1) than that of C60 1 system (K ∼ 2.1 × 104 dm3 mol−104
While UV Vis studies establish the ground state electronic interaction between fullerenes and 1 in absence and presence of AgNp, steady state fluorescence experiment enables us to determine the value of binding constant (K) for the fullerene-1 complexes in solution.
The negative value of binding energy suggests that the inhibitor is very stable and less prone to split apart.
All such structures that meet the rule of isolated quadrangles are close in value of binding energy.
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We considered a transcription factor to bind upstream of a gene if the corresponding p-value of binding was below 0.05 (as recommended by Harbison et al. [ 16]).
The average values of binding constants for the non-covalent complexes of C60 and C70 with 1 are determined to be ∼18,150 and ∼32,000 dm3 mol−1, respectively.
The shift of betweenness and closeness values of binding site residues in the mutant polymerase is relevant to the mechanism of drug resistance of VX-222 and ANA598.
The values of binding constant have been determined to be 4.1 × 105 M−1 and 4.8 × 105 M−1; and 5.2 × 105 M−1 and 5.6 × 105 M−1 for ETO and ETO cation free radical in phosphate buffer solutions of pH 4.5 and 7.4; respectively.
Moreover, the values of binding constant were found to be in the range of 103 M− 1, which is indicative of groove binding between ticlopidine and calf thymus DNA.
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