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Such differences may in part underlie the contrast in predictive value of activating KRAS and BRAF mutations.
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Regarding responsiveness, we focussed on the value of activated STAT5 in the nucleus (DpS nc), while the analysis of the fraction of activated receptors has been included in Sup.
Additionally, reduction of σ0 value of activated carbon is greater in the case of lower molecular weight of PAA.
Anticoagulation was provided with non-fractioned heparin, adjusting the dosage according to the value of activated partial thromboplastin time in the plasma.
The prognostic value of activated tissue Akt in relation to HER2/neu overexpression for DFS was determined.
Hence, the lack of prognostic value for p-Akt-s473 expression in the present study may reflect the balanced prognostic value of activated Akt1 and Akt2.
High levels (greater than the median value) of activated c-Src expression in the cytoplasm or nucleus was therefore detectable in over 50% (n=153) of all ER-positive breast tumours analysed.
The aims of this study were to further analyze the relationships the mTOR expression with the prognosis value of activated mTOR (p-mTOR), the effect of RAD001 on the growth and cell cycle of human gastric cancer cells in vitro and determine whether gastric cancer is a good candidate for target therapy with mTOR inhibitors.
In summary, we conducted systematical research to mTOR in gastric cancer, indicating the relationships the expression with the prognosis value of activated mTOR (p-mTOR) in vivo, the effect of RAD001 and the part of mechanisms in gastric cancer cells in vitro.
High expression level (above the median value) of activated c-Src within the nucleus of tumour cells was significantly associated with improved overall survival (P=0.047) and decreased recurrence in tamoxifen-treated patients (P=0.02), Figure 3A and B. On Cox regression analysis this was not shown to be independent of survival or recurrence.
A range of values of activating and repressing parameters ω1, ω2, ω3, respectively on entries (1, 4), (1, 5) and (1, 6) in expression (17) was considered for analyzing the stability behavior of the network.
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