The study started when patients were sedated with a constant value of the stroke volume in semi-recumbent position for 10 min and the first set of hemodynamic measurements was recorded, including the heart rate, systemic arterial pressure, diastolic arterial pressure, mean arterial pressure, central venous pressure, stroke volume, PtcO2 and PtcCO2.
The diagnosis of stroke has previously been validated in the Danish registry; with a positive predictive value of ischaemic stroke of 97%.
Patients received additional fluid challenges with colloid solution to achieve an optimal value of stroke volume in an identical fashion to patients in the SV group.
By unilaterally switching the indexation from RPI to CPI, the government has already stripped up to 20% off the value of pensions at a stroke.
As shown in Fig. 3 and Additional file 1: Table SDC3, the area under the ROC curves constructed for the value of CI, stroke volume and global end diastolic at baseline was significantly lower than that of PLR-induced changes in CI.
Other investigators have demonstrated the value of using stroke volume variation to determine intraoperative fluid administration during high risk surgery [ 17].
18 The positive predictive value of acute stroke diagnoses in the DNPR is 97% for AIS, 74% for ICH, and 67% for SAH.
The outcome diagnoses of stroke and pulmonary embolism have previously been validated in the registry; the positive predictive value of ischaemic stroke (I63) was 97%, haemorrhagic strokes only comprised 5.8% of the unspecified strokes (I64), and pulmonary embolism (I26) had a positive predictive value of 82.1%.
We repeated the analyses restricted to patients with a CT or MRI scan registered in the DNPR during their hospitalization, in order to increase the positive predicted value of the stroke diagnosis.
The positive predictive value of fatal stroke in mortality statistics was slightly improved when autopsy results were available, but the change of sensitivity was not statistically significant (based on the overlapping of confidence intervals).
