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PMA data for these global methylation assays are reported as a percentage of methylated reference (PMR) value, normalizing the MI of each sample to the MI of the universally methylated reference (UM.L) DNA [25].
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This approximation is referred to as expected value normalized variance approximation (ENVA).
(iii) is computed as mean of the maximum and minimum value normalized by the global mean.
The slope value normalized the individual peptide ratios.
In 19 cases CA125 value normalized during treatment.
If the value normalizes the subject will continue the halved dose.
Values normalized to GAPDH before normalization to pooled control human muscle RNA.
Values normalized after 24 h in 84.2%.
b Values normalized to reference time T0=75 min (dashed red line).
The solid and dashed lines denoted the expression values normalized by two different methods.
The algorithm calculated base error probabilities based on their quality values, normalized to a PHRED scale.
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