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In fact, David Meltzer, an economist and a primary-care physician at the University of Chicago, may be the first and only researcher in the country trying to quantify that relationship's value in a randomized clinical trial, the most rigorous scientific method.
Participants then rated each value (in a randomized order) along four dimensions using a 6-point Likert scale (see below).
Epigenetic silencing of the MGMT gene encoding a DNA repair enzyme was recently found to be of predictive value in a randomized clinical trial for newly diagnosed glioblastoma testing the addition of the alkylating agent temozolomide to standard radiotherapy.
There is also evidence that serum 25(OH D concentrations above 40 ng/ml might be considered optimal during pregnancy since optimal production of 1,25-dihydroxyvitamin D was achieved above this value in a randomized controlled trial with pregnant women., No adverse effects on calcium metabolism or other parameters were apparent in pregnant women taking 4000 IU/d of vitamin D3.
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Contrary to findings reported for mobile phone calls [58] and microblogging [57] we did not observe a higher tendency of female users to form gender homogeneous triangles, while we observed a stronger deviation from the expected values in a randomized model for the number of male-only triangles.
Here, we probe the behavioral and neural effects of MT on value signals in vmPFC in a randomized longitudinal design of 8 weeks of MT on an initially naïve subject cohort.
Results support the value of a randomized controlled trial to further evaluate the SAFETY intervention.
For the downstream regions, the lowest p-value that we observed in a randomized set was 10−4, much higher than 1.8×10−13 observed for the real data set.
For comparison, the lowest p-value that we observed in a randomized set for the motif that was most enriched in the real data set (TTTTNTAA, p = 1.3×10−14) was 1.4×10−10.
To determine the exact value of SA, a randomized controlled trial in which SA is compared to surgery would be ideal.
"The point that we want to get across was the value in doing randomized trials," he said.
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