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More advanced methods attempt to match data-set specific parameters of the expression value distributions between input sets.
The significantly different correlation value distributions between directly and indirectly linked metabolites barely provide a good quantification of the actual discrimination accuracy of this feature.
Specifically, we required minimally a three-fold difference of signals between lowest and highest expression values, in addition to the demonstrated difference in signal value distributions between nonaggressive and aggressive cases.
Hence, separation of feature value distributions between the samples from different states will be relatively clearer, and thus classification accuracy as a measure of feature set's discriminatory power can be biased.
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A chi-square trend test revealed significant differences of the beta value distribution between all eight groups (on autosomes) and the total CpGs on the array.
There was some evidence of a difference in Ct value distribution between electron microscopy positive IID cases in these two age groups (rank sum test p = 0.036), with the median in children aged less than five years at Ct value 23 and at Ct value 25 for older children and adults (Table 2).
To obtain a voxel set that objectively fully contains the lung for comparison of the dark-field CT gray-value distributions between the mice, the threshold-based segmentations (optimized for visual appearance) were strongly dilated, so that a volume that comprises lung and partly surrounding non-scattering soft tissue was achieved.
To compare the performance of our integrative pyramid analysis to that of traditional GWAS, we compared the p-value distribution between these analytic approaches.
The 95th percentile of the LD r values distribution between non-syntenic markers was used as a threshold to distinguish the LD mostly attributable to linkage from the background LD caused by population structure [ 75].
We hypothesize that if the component is key to defining the system's phenotype, then its value distributions will be separable between the observations from different phenotypes.
The expression values of the exon-SNP-methyl triplets tested were permuted 1000 times to assess the expected p value distributions for the interaction between genetic variation and DNA methylation on gene expression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com