Therefore, Hsps may constitute valuable tier-1 biomarkers among the broad-response biomarkers that are being used for preliminary screening of complex environments in in vitro cells (Bierkens 2000).
Specific biomarkers are, for example, valuable in second tier assessments to detect and identify the effects of specific types of substances in impacted locations.
The homology and EST data provided a second tier of valuable information.
The properties of heat shock proteins as (i) part of the cellular protective machinery, (ii) inducible nature against a wide range of chemicals, and (iii) higher conservation across the taxa have proven them to be valuable as a first tier biomarker in risk assessment.
Cable operators say they're not giving any new nationally distributed cable networks a slot on expanded basic (which reaches more than 95% of subscribers on a cable system) because that analog tier is too valuable.
Considering the importance of meiofauna for benthic ecosystems, the microcosm approach using natural meiobenthic communities might be a valuable addition as a higher tier approach in ecological risk assessment, providing highly relevant ecological information on the toxicity of contaminated sediments.
"As proud as we are to sell the top-tier fuels that we do," she adds -- echoing a line from 76 ads about its status as "top-tier gas" — "the thing most valuable to us about the car is the person behind the wheel".
Because the site had started attracting a small, but valuable audience of young women from top-tier universities, employers reached out wondering how they could recruit some of these visitors.
Access to these top recruits is extremely valuable, and Stanford, like many other top-tier colleges, sells it to the highest bidder.
This was the culmination of a season of growth: from top-tier recruit, to overweight freshman, to valuable contributor, to, now finally, starter.
