Fragment-based design might deliver valuable starting points for the discovery of novel MBL inhibitors.
These compounds represent novel valuable starting point in the development of novel antibacterial agents.
Using templates provides a valuable starting point acting as a reminder to researchers to record specific information.
Such a library provides valuable starting data for subsequent in silico experiments that aim to identify more potentially active leads.
The authors expect to provide valuable starting points for designers of sorption or thermochemical energy storage units.
In our opinion, the compounds encountered on and around a morphing path could provide valuable starting points for future in silico or in vitro experiments aimed at assessing the biological activities of such compounds.
Such valuable starting points for lead discovery can be obtained by pharmacophore-based similarity searching, which has emerged as a preferred concept for retrieving novel bioactive chemotypes with minimal experimental effort.
The Ala82Phe and Ala82Trp mutants are also very much more effective catalysts of indole hydroxylation than the wild-type enzyme, suggesting that they will be valuable starting points for the design of mutants to catalyse synthetically useful hydroxylation reactions.
Nonetheless, the interactome studies have proven to be very valuable starting points for predicting functions of unknown proteins when found to interact with known partners.
In search of bioactive compounds, many exogenous natural products were demonstrated to have valuable starting points for medicinal chemistry.
Subsets of genes expressed in mammalian stem cells that cause phenotypes in Drosophila Nbs may represent valuable starting points for functional analyses and are provided in Table S2.
