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The basal fungus Mucor circinelloides has become, in recent years, a valuable model to study RNA-mediated gene silencing or RNA interference (RNAi).
High fecundity genotypes in sheep are a valuable model to study the physiological mechanisms underlying follicle selection and the control of ovulation rate.
Thus, these bacterial artificial chromosome humanized HO-1 mice are a valuable model to study the human HO-1 gene, providing insight to the in vivo architecture of the gene in acute kidney injury and other diseases.
These findings provide new insights into the role of α-syn in the pathogenesis of PD and could represent a novel and valuable model to study DA-related neurodegeneration.
It seems that rabbits constitute a valuable model to study the mechanisms of HEV replication and pathogenesis.
Antlers are a valuable model to study mechanisms of organ regeneration and rapid tissue growth [10], [11].
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VT2OcKO mice and conditional ES cells may represent valuable models to study and better understand this process.
We have cloned the ASAP orthologs in mouse and Xenopus, two valuable models to study the function of ASAP.
As specific cohorts, nonagenarians and centenarians are always considered as the most valuable models to study the mechanisms involved in human aging and longevity [ 6].
- Long-term, independent exposures of these cell lines to arsenite (AsIII), monomethylarsonous acid (MMAIII) and cadmium (CdII) induced hyperproliferation, conferred anchorage independent growth and tumorigenicity.,,,, The resulting tumorigenic cell lines provide valuable models to study the epigenetic component of arsenical or cadmium-induced malignant transformation in relevant target tissues.
Furthermore, it demonstrates that Medaka provides a valuable experimental model to study molecular mechanisms for compensating microgravity induced bone loss.
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