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Our experiments have also shown that sex-mismatched parabiosis is a valuable model for testing how sex-specific changes in systemic factors with age can influence stem cell and organ function.
This study provides new insight into the mechanism of an ASD-associated gene and suggests that the Cntnap2-knockout mouse is a valuable model for testing candidate drugs for these disorders.
This result together with the demonstration that similar efficiency can also be achieved for skipping human dystrophin exon 50 in the hDMD/mdx mouse clearly indicate that the hDMD/mdx mouse becomes a valuable model for testing AOs targeting human dystrophin when Vivo-PMO is used.
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Transgenic mice are valuable models for testing cytotoxic chemotherapy regimens.
We propose that infection at mid-gestation (day 7) in BALB/c mice and its study during the post-natal period constitutes a valuable experimental model for testing new chemotherapeutic agents and vaccines designed to protect against congenital neosporosis, in order to select effective protocols before its use on bovine.
This highlights that while the pig is a valuable model for developing and testing surgical procedures, it is not a direct substitute for human studies.
These results indicate that precision-cut human liver slices are relatively stable during 24 h of incubation and represent a valuable model for human in vitro hepatotoxicity testing despite the human inter-individual variability.
Non-human primates as phylogenetically the closest relatives to man and naturally susceptible to M. tuberculosis infection comprise a valuable model for investigating aspects of TB disease and protection [17] [20], and for preclinical TB vaccine testing [21] [24].
The mouse is a valuable model for understanding human iron disorders.
Thus, sperm can be considered a valuable model for studying exocytosis.
The canine model is a valuable model for biomarker studies in OA.
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