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This is a valuable hypothesis related to fundamental understanding of how the immune system is designed to counteract bacterial pathogenicity and should be further tested.
This will enable valuable hypothesis generation which can be tested within the wider longitudinal study which is powered to examine causal processes.
While additional studies will be required to confirm the utility of the ITS marker for inferring demographic histories of lichenized ascomycetes using Bayesian skyline analyses, our study provides a valuable "hypothesis generating" approach for assessing historical factors driving population dynamics in lichen-forming fungi.
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However, population-specific dietary habits and/or environmental exposures may still be valuable hypotheses to explain the specific pattern of NAT2 haplotype frequencies in this geographic area.
They often provide valuable hypotheses, but none are perfect.
The correlations of particular words with cellular functions or expression patterns provide valuable hypotheses for further experimentation.
Second, while previous studies have generated valuable hypotheses on causal relationships between HRH and health outcomes [ 14], their cross-sectional design inhibits deeper investigation.
These editors perceived a need to provide intensive support to authors because they recognized that researchers often had valuable hypotheses and data but lacked the skills to present them.
Remarkably, the six functions described in the literature were distributed on five different clades, thus giving valuable hypotheses regarding the putative function of the orthologues or paralogues in other Angiosperm species.
Because a common evolutionary origin leaves distinct imprints on the sequences, structures and function of protein molecules, comparative computational methods supported by the accumulating biomolecular data often offer shortcuts to obtaining valuable hypotheses about a protein that cut the cost and time associated with experimental work.
The question was essentially: is it better to perform larger PoC trials to minimize the adverse consequences of type I and II statistical errors, or to perform smaller PoC trials so that more valuable hypotheses can be tested under a fixed PoC trial budget?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com