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Although their role in the pathogenicity of the optic neuropathy affecting these patients needs to be evaluated further, we believe that these unique anti-optic nerve AAbs can be valuable disease markers.
This together with the strong resemblance between the eye oscillations of bel rev and CN in human patients with defective retinotectal projection [5] emphasizes that bel rev is a valuable disease model for CN in humans.
Hyperferritinemia is proved to be a valuable disease marker of HLH.
Among genetic diseases from which iPS cells have been derived, spinal muscular athrophy (SMA) looks to be one of the most promising to generate a valuable disease modeling.
Though not without challenges, syndromic surveillance has the potential to serve as a valuable disease detection tool in resource-limited settings.
In conclusion, analysis of urine peptides can provide valuable disease and renal injury specific biomarkers and provide additional insights into the underlying (patho) physical processes.
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Moreover, a mere "omics" approach of human tissue samples frequently leads into a "data jungle" hiding valuable disease-relevant clues.
Additionally as a non-host of many important cereal diseases, they are able to provide a valuable disease-break from pathogens such as Take-all (Gaeumannomyces graminis), crown rot (Fusarium graminearum) and cereal cyst nematode (Heterodera avenae) [ 4].
This further supports the role of OPG as a valuable CV disease risk biomarker in chronic inflammatory rheumatic diseases such as AS.
4 Clinical trial simulation cannot replace the RCT, but could be valuable in disease areas such as type 2 diabetes and cardiovascular disease (CVD), where trial protocols are often complex, and powering trials require large populations with multiyear follow-up.
However, there are instances where DWI is especially valuable when disease is not readily visible on otomicroscopic examination, such as disease extension into the petrous apex (Fig. 13) or mastoid tip (Fig. 14), disease deep to an obliterated cavity, in a small reconstructed middle ear cavity or medial to an opaque tympanic membrane reconstruction [42].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com