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Compound 2, the newly synthesized N-oxide metabolite in N,N,N′-trimethylethylenediamine side chain of osimertinib, showed a comparable kinase selectivity in vitro and a slightly better antitumor efficacy in vivo to osimertinib, making it valuable and suitable for the potential lung cancer therapy.
Therefore, it is a valuable and suitable tool to evaluate the efficacy of new vaccination strategies and antiviral therapies for the prevention or treatment of human OPV infections.
In this regard, our results show that EST databases are a valuable and suitable source for SSRs discovery.
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The architecture of the encoder is simple and suitable for valuable applications in the development of low cost non-processor based multimedia products.
Embedding owner's watermarks into the digital multimedia contents usually results in a slight degradation, which is not suitable for valuable and sensitive digital multimedia contents such as artistic, medical, and military images.
Wetness indices are valuable predictors of potential tree growth rates, vulnerability to wildfires, and suitable habitats for a number of vertebrate species.
FPs considered cognitive behavioural therapy (CBT) and problem solving therapy (PST) as valuable interventions, suitable in family practice, but experienced a deficit in skills to apply such techniques.
YINS will develop a process whereby affiliated faculty might identify valuable IP suitable for patent or other sorts of protections.
These mice models are a valuable resource suitable for some types of experiments.
Finally, a novel set of haplotypes and microsatellite marker alleles specifically related to important texture components are presented as valuable markers suitable for marker assisted parent selection (MAPS) as well to assist traditional breeding towards the selection of novel apple accessions characterized by superior fruit quality properties.
While not suitable for smoking, hemp seeds can be a valuable and inexpensive food source.
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