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In fact, one could make a strong case that Silicon Valley itself went through a crisis of succession in the late 1970s and early 1980s, when the fiery first generation of Valley chip guys gave way not only to the bespoked bean counters I just listed, but to a whole era of decent, well-educated and ineffectual entrepreneurs.
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The parallels between the evolution of the nascent gene sequencing industry and the Valley's chip makers are striking.
Founded by veterans of the Valley's chip and hard-drive industries, these companies attracted billions of dollars in venture capital investment on the hope that their advanced "thin film" technology would make them the Intels and Apples of the global solar industry.
The venture backers were Valley blue chips including Kleiner Perkins Caufield & Byers, and Google Ventures.
First stop might be Walker's Wagon Wheel, a bar in Mountain View, where the Valley's original chip engineers could be found in the 1960's.
National Semiconductor, another of the Valley's large chip companies, was downgraded last week by Jonathan Joseph of Salomon Smith Barney, who expressed worry in a note to investors that the cellphone market might be softening.
That doesn't mean that hardware is dead – there's plenty of Valley innovation in chips (e.g. Arm and Apple A4), Computers (e.g. the iPad), and other physical products.
Riding the exponentially increasing power of the computer chip, the valley has demonstrated the ability to reinvent itself relentlessly.
Start with lime vodka-cured salmon stack with lattice chips, Yarra Valley salmon eggs, creme fraiche and citrus oil, followed by Sichuan peppered duck with steamed rice noodle roll, wok-fried Asian greens and infused Chinese rice-wine dressing.
He zipped a beautiful chip from the valley of the par-five that stopped three feet from the cup.
Then there was Louis Oosthuizen's wonderful chip over the Valley of Sin at the 18th to give him a six-foot birdie and a place in the play-off.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com