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Individual physician judgment compromises the internal validity of the trial, and randomization is therefore necessary to allow valid inferences to be drawn.
The parties vigorously dispute the validity of the trial court's finding on how discriminating the average buyer actually is.
For many conference proceedings it would be difficult to assess the internal and external validity of the trial based on the information reported.
Pfizer said any discrepancies noted by FDA "did not compromise the validity of the trial or its conclusions". The FDA would not discuss why it never approved marketing Trovan for children--such specifics are considered corporate secrets.
The pragmatically-oriented RCT aims at establishing the superiority of a treatment over another, the goal being to maximize the external validity of the trial (that is, its application in current practice).
We compared characteristics and outcomes of children enrolled in a randomized controlled trial (RCT) comparing oral amoxicillin and benzyl penicillin for the treatment of chest indrawing pneumonia vs. children who received routine care to determine the external validity of the trial results.
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Until authors of trials improve their reporting of blinding, readers will have difficulty in judging the validity of the trials that they may wish to use to guide their clinical practice.
The reviewers used eight criteria to assess the validity of the trials findings and provided reasons for selection of the criteria based on design issues specific to adherence enhancing intervention studies [ 22] and the Consort Statement [ 23].
The results of adjusted indirect comparisons should be interpreted with caution however and the internal and external validity of the trials involved examined carefully, to investigate potential causes of discrepancy.
There are several challenging aspects to consider in evaluating an IBI the population, the setting and the internal validity of the research trial [ 28].
Mr. Abe, who has cast doubt on the validity of the Tokyo trials in the past, avoided elaborating on his views in the Indian Parliament or during his 20-minute meeting with Judge Pal's son, Prasanta.
More suggestions(15)
validity of the charge
applicability of the trial
relevance of the trial
merit of the trial
appropriateness of the trial
adequacy of the trial
term of the trial
validity of the questionnaire
validity of the question
validity of the algorithm
validity of the modification
validity of the satisfaction
validity of the model
validity of the change
validity of the information
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com