In order to check the validity of the annotations and thus see whether the reliability would increase if more annotators had been employed for the annotation task, we selected one movie, namely "DEP," which was annotated by five more users, thus eight in total.
The clinical validity of the annotations has been ensured by two of the team members—i.e.e
Results: We demonstrate that a machine-learning approach using only network topological features can successfully predict the validity of enzyme annotations.
When a high level of certainty about the validity of an annotation is required, variants could be annotated with two software tools and variants with differing annotations flagged to be treated with caution.
Using the data from H-InvDB, we performed several analyses of the annotated complexes to increase the validity of our annotation.
In terms of evaluating the validity of the annotation scheme, the resulting reliability indicates how well the annotation scheme captures the truth of the phenomenon being studied [ 34].
Unlike in the simulated data case, where the validity of each annotation was known by design, the consistency of C2 gene set annotations for the p53 data could only be inferred indirectly.
COG was used to further evaluate the completeness of the tea plant transcriptome libraries and the validity of the annotation.
In order to test the validity of the annotation of chickpea tag sequences through homologies with other legumes, 7,500 chickpea EST sequences deposited in the NCBI data bank were used to generate virtual 26 bp tags.
In order to test the validity of the annotation of chickpea 26 pb tags through sequence homology with other legumes, virtual tags generated from chickpea EST sequences deposited in the NCBI data bank were extracted, and their direct annotation was compared with the annotation of longer homologous ESTs from the model legume M. truncatula.
So when there is not enough time to visually annotate every profile, an annotated region database is still useful for checking the validity of an automatic annotation algorithm.
