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38 This tool uses three broad categories to address study validity, methodology, recruitment styles and appropriateness, validation of exposure status and measurements, confounding variables and study outcome.
Therefore, the main purpose of this review is to identify the existing literature on clinical studies utilizing MSCs or ASCs to treat oral bone defects and to critically analyze their validity, methodology, and outcomes.
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Internal validity, study methodology, and external validity were assessed.
The validity of methodology, its appropriateness and reporting of results were assessed (20, 21).
Early acquisition of such evidence requires attention to good study design and validity of methodology.
As validity of methodology, the performance of our method was compared with traditional methods.
To ensure external validity, the methodology should be replicated in other institutions equipped with EMRs and using the expertise of local clinical experts.
Our preliminary validation studies indicating high reproducibility of results for urinary L/R recovery both in celiacs and in healthy controls, and the ability of the test to discriminate healthy controls from CD patients on gluten containing diet, support the validity of methodology used for measurements.
Many debates remain around risk analysis in relation to validity, practicality, methodologies and other areas [20].
Established classification rates have demonstrated the validity of the methodology on small scenes; a logical extension was to apply the methodology to whole slide images via scanning technology.
To demonstrate the validity of the methodology even at lower Reynolds numbers and validate the process of designing micro rotor for wind tunnel testing, two micro rotors with different scales were designed.
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