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More validation will be required to hone in on specific molecular processes.
Biochemical evidence of interactions with RBPs and other experimental validation will be required to confirm co-regulation of these transcripts.
To resolve whether HMMSplicer non-canonical junctions are false positives or novel instances, further experimental validation will be required.
Thus, further validation will be required by examining information pertaining to postoperative swallowing function.
In order to generalise our results, external validation will be required [ 36].
25 Further clinical validation will be required to confirm these findings and eliminate possible confounding variables.
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Further functional validations will be required to determine antisense-mediated regulation for these key protein-coding genes.
Validation studies will be required to address this question.
Characterization and validation studies will be required in order to carefully assess the effect of such variability on segmentation performance.
Additional validation studies will be required in order to assess the usefulness of this instrument in other populations and for different QOL and other outcomes.
However, additional confirmatory studies in validation sets will be required in order to actualise the possible benefits illustrated by the results of this study.
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