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Score validation was executed at the Detroit Medical Center (DMC) health system in Southeast Michigan, which consists of 2200 inpatient beds.
A partial validation was executed and all requirements for acceptance, as defined in the FDA and EMA guidelines on bioanalytical method validation [ 25, 26] were fulfilled.
A partial validation was executed and all requirements for acceptance, as defined in the FDA and EMA guidelines on Bioanalytical Method Validation [ 17, 18] were fulfilled.
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For both classification and regression, 10-fold cross-validation was executed multiple times, in order to obtain a Gaussian distribution that could be compared with a t-statistic (adjusted for sample overlap and multiple testing), useful in model comparison or model selection (Nadeau et al., 2000).
Ebram Laboratory returned the email stating that they did not have any technical report at the time, and the only validation process was executed by CGLAB (N° 03/06) (Coordenação Geral de Laboratórios de Saúde Pública - or General Coordination of Public Health Laboratories, which is a coordination in the Brazilian Epidemiologic Surveillance Department).
Hence, splitting into the training and independent test sets as well as to the cross-validation folds was executed according to one of these three evaluation schemes for different experiments.
Validation with RT-PCR was executed as previously described [ 47], with the Applied Biosystems 7900HT Sequence Detection System used for the Taqman assays, and downstream analysis performed with SDS 2.2 software.
To validate the three-dimensional model, 3-factor confirmatory WLS factor analysis was executed in validation sample B. The 3-factor model showed good fit to the data (CFI =.97; TLI =.97; RMSEA =.023) when factors were allowed to correlate (r(Physics, Chemistry) =.76; r(Physics, Biology) =.57; r(Chemistry, Biology) =.51).
Hypatius was executed.
Spenkelink was executed.
He was executed.
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