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Under optimum conditions, the method exhibits good performance in terms of linearity and precision (RSD < 9.2%), with recoveries above 71% and limits of detection (LODs) within the range 0.5 1.8 pg g−1 dry weight (d.w).. Method validation was demonstrated through the analysis of environmental sediment samples in which PBDEs were detected and quantified.
LGMN was one of such genes and upon further validation was demonstrated to be regulated by nuclear Ca2+ signals at the transcriptional level.
The utility of inducible shRNA expression for in vivo drug target validation was demonstrated by Xue and co-workers, who used a doxycycline-regulatable shRNA against Trp53 to establish a chimeric mouse model of liver cancer [ 40].
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Simulation validation is demonstrated with a preliminary architectural exploration study.
Experimental validation is demonstrated by two pseudo-elliptic fifth-order band-stop filters fabricated and measured in Ka and V bands.
Furthermore, complete systematic design validation is demonstrated by integration of the resonant actuator in a wind tunnel for a turbulence manipulation study.
Molecular correspondence of high- and low-risk outcome groups between training and validation datasets was demonstrated using Subclass Mapping.
The validation of this test was demonstrated by the stronger drive to chew a chocolate cookie than to chew a regular food pellet as a robust reduction of the chewing latency with the chocolate cookie when compared with the regular food.
Validation of assay precision was demonstrated by repeatability tests (Table 2).
Validation as an antiviral assay was demonstrated with two influenza antivirals, zanamivir and rimantadine.
It was no surprise then that functional validation of an AP2 factor was demonstrated in recent studies, which established the essential roles for Plasmodium berghei AP2 factors in the formation of ookinete and sporozoite developmental stages [77], [78].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com