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All the initial screening data (20% of each library) was then used to construct a predictor that was used to predict the remaining 80% of the screening library based on the confidence level indicated from the internal validation to give the highest gain.
Indel loci with minimum putative lengths of 250 - 2500 bp were chosen for validation to give PCR amplicons with convenient product sizes.
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The calibration, obtained after internal cross validation, proved to give values of coefficient of determination always higher than 0.95, ratio of performance to deviation higher than 4, and comparably reduced root mean squared error of cross validation.
We perform a cross-validation exercise to give an insight of the optimization of the experiment design for selected scenarios: we find that it is sufficient to use 100s values for the size of training set and that it is adequate to use as few as 15 K-L components.
A diagnostic signature pattern consisting of five biomarkers was developed and assessed using a cross-validation strategy to give high sensitivity and specificity.
We ran ten cross-validation replicates for each model and calculated the average AUC of the ten cross-validations (mean ± SD) to give a more robust estimate of predictive performance.
This method of validation provides important benefits in hardware prototyping: better validation environment and reduced time to give a real estimation for a large variety of applications.
The FE model was also analysed using CAPA 3D to give a validation of the results.
A research prototype called JAFF and a case study are presented to give first validation of this approach.
Clearly she had a hole inside her, her own lack of self-esteem, and soon she invited people around I hadn't seen in years to give her validation.
They take a vague, science sounding idea, and bolt it onto their product in order to give it some validation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com