Third, the high accuracy achieved by cross-platform validation obviates the need for secondary validation (Fig. 3, Supplementary Note 7).
We present a unique perspective on sequence assembly and validation, particularly the need to adjust the assembly parameters locally, rather than using global parameters for the entire genome.
The OOB acts as a tuning/validation set at each tree and is almost identical to a n-fold cross validation, removing the need for a set aside test or tune test.
Independent validation of this method is required prior to application in other studies and laboratories; we have provided a method for validation without the need for collection of specimens from healthy controls or further use of EM.
The main lesson from our validation process is the need for multiple validation strategies, including empirical validation.
Again, this model can be used as an ongoing validation method, minimizing the need for implementation validation.
Decide what validation the solution needs in your own mind to give you a clear "go/no-go" decision on its feasibility.
For both verification and validation, the process needs to be planned and organized in advance by trained and qualified personnel.
Other studies are necessary to continue validation of the needs according to the Disability Creation Process framework.
