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For completeness the HQ needs to be validated in general (including UK) populations, and validation should include test-retest and convergent validity.
In this context, validation should include three aspects: a description of the relevant uncertainties, quantitative measurement results and a qualitative judgment that considers the needs of users.
Cleaning validation should include at least three productions of the desired radiopharmaceutical, followed by three cleaning procedures.
Every validation should include an assessment of the test-retest reliability, preferably by using intra-class correlation coefficients.
Further validation should include alternative data collection methods (e.g., participant observation in healthcare organizations) and larger and more diverse samples.
The ongoing validation should include results of internal quality control, external quality assessment and nonconformities related to the test or technique as appropriate.
Similar(48)
Although a rigorous approach will be used to develop the model, including internal and external validation, stronger forms of validation may be required: future validation studies should include application in different geographic locations, and fully independent validation by independent investigators using alternative measurement of these risk factors in different population settings.
Future validation studies should include application in different geographic locations, and fully independent validation by independent investigators using alternative measurement of these risk factors in different population settings.
The validation protocol should include the acceptance criteria used to pass/fail individual runs and assess other validation experimental results.
The validation plan should include the general scope of the system including high-level design features, the personnel responsible for the validation, a timeline, and a summary of other supporting documentation that need to be addressed in order to use the system.
Thus, while current mouthguards would suffer from measurement errors in the worst-case unconstrained mandible condition, future mouthguards should be designed to account for these disturbances and future validation testing should include unconstrained mandibles to ensure proper accuracy.
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