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Therefore, the general aim of the present study is the development and validation (reliability and validity) of the ALTAIR software platform in order to analyse its utility in different clinical settings.
Further, 20 randomly selected papers were read in full to verify that our keyword search did not miss any information on validation, reliability, or quality control information.
In forward prediction, differences between models in terms of validation reliability of estimated direct genomic values were small but predictive power was consistently lowest for M1.
Several culture surfaces have recently been reported to meet many of these criteria although none of them have been widely implemented by the stem cell community due to issues with validation, reliability and expense.
The literature search was performed by using MEDLINE and PubMed electronic databases with the following key words: "intensive care", "critical care," "glucose," "sugar," "glycemic," "insulin," "Bland Altman," "agreement," "validation," "reliability," "accuracy," "correlation," "Clarke grid," and "bias".
The incorporation of surrogate and tumour pharmacodynamic markers into clinical trials has also highlighted the fact that assay validation, reliability and quality assurance need attention if results are to be interpretable (Colburn, 2003; Cummings et al, 2004).
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When ignoring this correction, the validation reliabilities of genomic predictions for CH bulls using the joint reference dataset were unrealistically high at 0.69, 0.54 and 0.60 for milk yield, fat yield and protein yield, respectively.
This perception is in part due to the smaller impact that females have on the next generation, but also due to the relatively small difference between the base PEV reliability of EBVP or EBVP&Y and the base PEV or validation reliabilities of EBVM.
Table 4 reports validation reliabilities of GEBV from the two single-step blending methods and DGVω from the GBLUP method with a polygenic effect (the adjusted GBLUP method is shown as an example) for the 16 traits, with a relative weight ω = 0.20.
In a follow-up investigation, they found that using breed- or subpopulation-specific allele frequencies to calculate the genomic relationship matrix (G) did not result in higher validation reliabilities, although accounting for specific allele frequencies in the calculation of G changed the estimated GBV of some individuals considerably [ 14].
Using five-fold cross-validation, reliabilities of genomic predictions of Chinese cows increased from 0.15, 0.12 and 0.15 to 0.26, 0.17 and 0.20 for milk yield, fat yield and protein yield, respectively.
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