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Validation of models has shown that besides comparing the model and the process output behaviour, additional measures considering also the model input error should be introduced for proper model validation related to the model use.
The first step is an accuracy evaluation, which consists of a design validation related to the scientific quality of MOTIFS and its selected indicators, and an output validation that is an evaluation of the information supplied by their output.
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How does the prediction error obtained in the outer loop of cross-validation relate to external validation?
The third stage of validation relates to data collection during routine production to continuously monitor the process.
In addition, two validation cases related to NASA aeronautics applications are presented: the 1st AIAA Sonic Boom Prediction Workshop test cases and a computational study of slat noise.
A series of independent validation experiments related to sheet metal forming were performed including a hole tension test, a conical and flat punch hole expansion test, and a hemispherical punch test.
This document is meant as an Appendix of Part B of the EANM "Guidelines on Good Radiopharmacy Practice GRPPP)" issued by the Radiopharmacy Committee of the EANM, covering the qualification and validation aspects related to the small-scale "in house" preparation of radiopharmaceuticals.
This approach is questioned by others, who note that in some cases the number of compounds is too limited to use this approach without renouncing a significant proportion in order to represent the real situation; furthermore, external validation is related to the specific list of compounds, which can represent a bias.
Yet, these techniques have deficiencies with respect to validation, principally related to speed, reproducibility, cost, and/or accessibility.
In this section we will present results of the validation procedures related to our main findings in this work.
Risk categories are assigned to allow interpretation of the ROR score by using pre-specified cutoffs (defined in a clinical validation study) related to risk of distant recurrence after 10 years [ 19].
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