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Although we did not perform any further validation regarding these pathways, these results should be intriguing to researchers in the relevant fields.
What arrived from last year is more of a validation regarding the phrase 'never quit.' " This year has presented a different challenge, requiring a burst of wins rather than a monthlong grind.
The method meets the International Conference on Harmonization guideline for analytical methods validation regarding specificity, linearity, accuracy, precision, specificity and robustness as required by health authorities and applied by industry while designing and marketing new drug products.
In addition to the language and terminology limitations, the group made the deliberate choice to examine content developed by entities formally associated with education and curriculum development, to establish a first level of validation regarding the content examined.
For each element in the marked list, it identifies the type of the element (according to the types defined in Sect. 3.2) and performs a validation regarding this type.
One of us (DG) independently reviewed the clinical vignettes for accuracy and validation regarding the study objectives.
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The second part of our validation regards the modular structure of the collaboration networks in terms of communities.
Thus, the external validation regards the only way to determine both the generalizability and the true predictive power of QSAR models for new chemicals.
From the experimental validations regarding the forces, frequencies, cavity visualizations and velocity distributions, the PANS model is shown to improve the predictive capability considerably, in comparison to the standard k − ɛ model, and also, it is observed the value of f1 in the PANS model has substantial influence on the predicting result.
A consideration of the optimal binding pose for the modelled ligands was out of the scope of this work, and further validations regarding conformational refinement of docked or aligned poses using the FMO method are in progress.
This paper proposes an evolutionary approach to designing an SVM-based classifier (named ESVM) by simultaneous optimization of automatic feature selection and parameter tuning using an intelligent genetic algorithm, combined with k-fold cross-validation regarded as an estimator of generalization ability.
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