Sentence examples for validation pathway from inspiring English sources

For this pathway no applicable validation pathway is available in KEGG.

There was general agreement regarding the need to move several of the assays further along the validation pathway, at least using a short list of reference compounds.

RJF carried out the cell line work, glycoprotein analysis, Western blot validation, pathway analysis, topological scoring analysis, RPPA data analysis, and prepared the manuscript.

As a suggestion the authors should consider community validation Pathway accessibility and distribution is described but it is not clear as to how these models are available in any format except web browsing.

Another possibility for testing the plausibility of inferred pathways – without the need for validation pathways – is to test if the inferred pathway can be associated with a certain biological process.

Following initial validation, pathways that include NAD synthetase 1 (NandYN1) and protein kinase B (AKT2) were hypothesized and experimentally tested to provide a mechanistic basis for AMPK regulation of cell migration and maintenance of cellular NAD+ concentrations during catabolic processes.

However, this systematic linkage will hardly be implemented because epidemiological and genetic information of disease events in animals follow different processing and validation pathways; the EMPRES-i disease event id is currently assigned after these paths have long parted.

At each iteration of cross-validation, pathway-level aggregation and feature selection were performed anew, as has been emphasized as being the correct practice of cross-validation [ 41, 42].

Recently, innovative 13C-MFA approaches have been developed based on parallel labeling experiments, the use of multiple isotopic tracers and integrated data analysis, that allow more rigorous validation of pathway models and improved quantification of metabolic fluxes.

We selected TNBC for functional validation as pathway deregulation is least understood in TNBC, and hence, no targeted therapy exists for this subtype.

In an independent validation approach, pathway analysis was performed on genes that were mutated in the published 38 primary MM cases (1429), revealing an enrichment of 2 adhesion-associated pathways among the 20 most significant gene sets, and 4 adhesion-associated pathways among the top 50 most significant gene sets (Supplementary Table S10).