Your English writing platform
Discover LudwigExact(3)
Opinions from three experienced mass spectrometrists were used to derive a set of chemistry-based criteria that could be applied to tandem mass spectra for selection between, and validation of, the database PSM search hits.
The creation and initial validation of the database, software, and the decision-making criteria is an iterative process requiring testing on a large number of patients and assessment of a large number of benign and malignant lesions.
Final validation of the database demonstrated that <7% of the drugs required modification (new data available since initial database construction or error correction) to one or more values in data cells ((HI: 6% (12 modified among 207 drugs), RI: 7% (14 modified among 206 drugs), DDI: 6% (15 modified among 271 drugs)).
Similar(9)
Using 10-fold cross-validation on the database of 283 cases, the highest area under the receiver operating characteristic (ROC) curve (AUC) was 0.84 from a support vector machine with 77.7% overall accuracy; the highest overall accuracy, 78.5%, was from a random forest with the AUC 0.83.
The validation part of the database is reserved for confirmation of single pre-specified hypotheses.
In five of them, the findings of the training data were selected for confirmation in the validation part of the database.
In one project, the "relapse and disability" project as described in section II (example 3), findings could not be confirmed in the validation part of the database.
In contrast, for spatial epidemiologic studies that rely on routine data sources, it is usually not possible to carry out detailed validation studies of the database.
Validation of the injury database by comparing it to the hospital's radiology archive and surgical database revealed an accuracy of 90% (Bergström et al. 2008).
As such, the validation of the PTAC database will include accuracy levels for variables being validated and sensitivity measures.
The screening and validation of this database are described in detail elsewhere (McCarthy et al. 2007).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com