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Their application allows full validation of methods to analyse the priority substances in "whole water" and the establishment of proficiency testing (PT) schemes [ 10, 11] to ensure that the results are correct, precise and comparable.
The Clinical Laboratory Standard Institute (CLSI) clearly phrased the demand for internal validation of immune assays as well as external validation in proficiency panels [ 28].
Finally, we propose provisional recommendations for the design and statistical treatment of validation and proficiency studies.
These results substantially contribute to the validation as well as localization of proficiency standards for non-native speakers on a global scale.
A central reference laboratory in Johannesburg, Republic of South Africa, assisted with the conduct of cross-validation studies which included the selection and shipment of proficiency panels of 60 samples from the reference centre to the sites for biochemistry, hematology and urinanalysis.
This article presents an overview of statistical methods used in validation and proficiency testing for qualitative testing in analytical chemistry, paying particular attention to interlaboratory study.
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Good clinical laboratory practice (GCLP) guidelines recommend both assay validation and proficiency testing for assays being used in clinical trials, and such testing is facilitated by the availability of large numbers of well-characterized test samples.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com