Initial results that were collected from dozens of experiments present validation for the proof of principle.
Dozens of experiments were executed with four subjects in order to present a proof of principle validation.
Concerns have been raised that this expansion of the screening offer is based on proof of principle rather than validation studies, and that with the rarity of most of these microdeletion syndromes, the PPV is expected to be low.
They also provide validation of one principle for the design of effective graphical displays, namely that graphics should not display more information than is required for the task at hand.
A real clinical case of nephroblastoma has served as a proof of principle study case, demonstrating the basics of an ongoing clinical adaptation and validation process.
Research is currently being conducted as part of the AQUAREC project, with the objective being the development and validation of design principles for water reuse systems.
In order to expedite and accelerate the realization of CPS in the field of precision agriculture it is necessary to develop methods, tools, hardware and software components based upon transdisciplinary approaches, along with validation of the principles via prototypes and test beds.
The validation of the principles and the suggested incentive models for use in Ontario took place at two meetings.
Overall, our results offer a proof-of-principle validation of a complementary personal shielding strategy in emergency situations in case of a SPE event.
These preclinical results, obtained after coinjection of [111In-DOTA]MG11 withethe NEP inhibitor PA, warrant further validation in a "proof-of-principle" study in patients.
To provide proof-of-principle validation of our functional predictions, we performed siRNA-mediated knockdown of the C-type lectin CLEC1A (Table S5A), which is downregulated 7-fold by HCMV and is a potential NK ligand by homology to CLEC2D.
