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We also assessed the representativeness of the study participants; methods for ascertaining exposure; comparability of exposure groups (including unexposed) in terms of age, sex, socioeconomic status, non-response bias, health outcomes, determination, and validation of outcomes; internal validity; and assessment and addressing of confounding factors.
Progress will be tracked using novel connected-health technologies that will serve both as motivation for patients and as validation of outcomes.
Nevertheless, these findings need to be confirmed in studies with longer follow-up time, validation of outcomes, and data on time of onset of disease.
Nevertheless, these findings need to be investigated further in studies with longer follow-up time, validation of outcomes and data regarding time of onset.
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Development and validation of outcome measures are important, and predictors of outcome and effects in patient subgroups, especially elderly and neurologically impaired patients, should also be investigated.
Validation of outcome measures is not a single project.
Fundamental considerations rather than statistical inference should guide the validation of outcome measures.
Validation of outcome assessments is a vague playing field where clear guidance is lacking.
This report called for further development and validation of outcome measures [ 1].
35 This tool includes the assessment of study content, method of determining exposure status, comparability of the exposed versus non-exposed group, validation of outcome measures and generalisability.
The choice of the main dependent variable, MSBQ ≥ 5, was based on the results of a validation of outcome measurements in the current sciatica cohort [ 29].
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