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Another genomic resource, radiation hybrid (RH) maps, played a pivotal role in the process of mapping animal genomes and validation of draft assemblies of the genome sequence, especially in mammals [ 8– 11].
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OMJ participated in the training of the research assistants, validation of the transcripts, drafting and revising this manuscript.
TM conceived the study, led the study design, data collection, analysis and interpretation of the data and drafting the paper; MO, AG and PB participated in the study design, data collection, analysis and interpretation of the data and drafting the paper; CL, AOA and VD participated in the study design, interpretation and validation of the data and drafting the paper.
SS carried out all FT-related experiments, manual data validation, drafting of the manuscript and contributed substantially to the design of the data analysis tools.
AA contributed to the acquisition and interpretation of data concerning validation of the model, to drafting corresponding paragraphs in the manuscript and its critical revision.
NJO conceived the method, designed and carried out the validation of the study and drafted the manuscript; MF was involved in the conception, design and supervision of the method development.
The high level of accuracy (according to functional or sequence homology) between the experimental results and our predictions serves as a validation of iMLTC806cdf as a mature draft metabolic network and increases our confidence in the list of predicted essential genes.
The first two stages are integral to the process of psychometric development through the application of draft tools to a construction and validation sample (see below).
SRA contributed to study design, validation of gene expression and manuscript drafting.
BNA carried out most of the work described here including conception of experiments, analysis and interpretation of data, functional characterization and validation of differentially expressed genes and drafting the manuscript.
The first workshop was meant for context analysis and design of draft scenarios, while the second was aimed at scenario analysis and validation.
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