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Prior validation of concordance was obtained through direct comparison at school of visual acuity results obtained by teachers and by ophthalmic assistants for the same children.
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Simultaneous utilization of RNA-seq and gene chip assays to measure expression of the same genes is supported by the recent validation of high concordance between these technologies [ 28].
Our results indicate that automated HER2 FISH is a reliable method to determine the HER2 gene amplification status in breast carcinomas and fulfills ASCO/CAP requirements for test validation of >95% concordance for amplified versus non-amplified cases [ 2].
Internal Victorian Infectious Diseases Reference Laboratory validation confirmed concordance of results using these tests, and both produced highly reactive results in this case series.
Improvement, concordance and validation of a simple, easy and standard definition of neonatal near miss is required.
In external validation of the Kattan model, a concordance index of 0.76 was reported in two separate studies (Mariani et al, 2005; Eilber and Kattan, 2007), a concordance index of 0.77 was present in our validation series.
Vastesaeger et al. [ 43], in concordance with validation of the ASDAS [ 11], have demonstrated that ASDAS discriminate better than BASDAI in patients with elevated CRP and was equal to BASDAI in patients with normal CRP.
The validation of representative miRNAs confirms cross-platform concordance and the relative utility of the signatures identified.
Of the 11 genes tested, 8 were found to be concordant in the RQ-RT-PCR validation (73% concordance rate).
Mean concordance refers to an average of concordance index (C) estimates calculated in each of 10,000 cross-validation simulation trials (see Methods).
It should also be noted that some criteria of concordance with CCPGO recommendations, e.g., assessing readiness to change and realistic weight loss goals, lack empirical validation.
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