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The copulas that specify the dependence structure underlying the joint probability distribution over random fields are not provided and a Gaussian dependence structure is assumed without proper validation in practice.
Note that λ is a parameter that can be optimized through cross validation in practice.
Up until now, the draft set had been based on literature and expert opinion and hence needed operationalization and validation in practice, after which final adjustments could be made.
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These findings need validation in clinical practice.
However, the optimal interventions obtained by the MDP theory here require further validation in clinical practice.
However, these revised criteria still require further investigation and validation in clinical practice [ 42].
However, the optimal interventions obtained by the MDPs in this study require further validation in clinical practice.
We chose an immunoturbidimetric assay due to the fast assay time (10 minutes), a platform compatible with most analysers available in UK laboratories [ 30, 31] and a wide measuring range (25 to 5000 ng/mL) that will allow easy validation in clinical practice.
As a result of this intrinsic self-validation, LDA has in practice proven to be exceptionally reliable.
Computing time is important, particularly for cross-validation and implementation in practice which requires frequent re-estimation of breeding values.
Previous works in this area lack validation in the actual practice of AK sharing.
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