Sentence examples for validation in human from inspiring English sources

We also illustrate the use of the network in prioritizing amyloid- and cognition-associated genes for in vitro validation in human neurons and astrocytes.

In this study, we demonstrate the utility of the CRISPR/Cas9 genome engineering system for drug target validation in human cells.

These observations support the evaluation of cell turnover as a biomarker of cancer risk and indicator of prevention/treatment efficacy in preclinical models and warrant validation in human breast cancer.

The high quality of the DPiM and its usefulness as a paradigm for metazoan proteomes are apparent from the recovery of many known complexes, significant enrichment for shared functional attributes, and validation in human cells.

Until further validation in human studies, the implications of this work for patient care remain unclear.

More recently, the validation in human beings came from an autopsy study in which the value of EVLWI measured by transpulmonary thermodilution before death well correlated with the value obtained by gravimetry after autopsy [9].

Schoeller, D. A. et al. Energy expenditure by doubly labeled water - validation in humans and proposed calculation.

First, the translatability of our results to human scans was inferred, but not systematically tested: a prospective validation in humans is warranted, as while the reduction of dose exposure should be that observed in pigs, its absolute value might slightly differ.

Nonetheless, this finding awaits validation in humans.

Analyses aimed at the discovery of new biomarkers carried out in relevant animal models reaching different stages of validation in humans were discussed in a recent review [ 72].

To date, however, very few of these findings have resulted in target validation in humans or successful translation to disease-modifying therapies.