These latter two practices also supported the integration of newly validated role components.
Negotiated joining both accommodates open-ended roles and can promote adaptability by stimulating ongoing adjustments to group structure and goals, which is an unintended side effect of integrating newly validated role components.
Although EGFR is the only ErbB family member with a clinically validated role in CRC, there is a wide variation in the expression level (from 8to100%0%) of EGFR and there is no data regarding pEGFR localization by immunohistochemical analysis [ 4].
This is also true of the lung, where several studies have already implicated and validated roles for microRNA in early lung development.
Although echocardiography, positron emission tomography (PET), and nuclear imaging have validated roles, recent advances in cardiac magnetic resonance (CMR) technology and availability have led to increased experience in CMR for identification of myocardial viability.
For instance, the cluster of genes activated by mating pheromone was enriched for genes whose S. cerevisiae orthologs have experimentally validated roles in response to pheromone, conjugation, and karyogamy.
Altenhofer, S. et al. The NOX toolbox: validating the role of NADPH oxidases in physiology and disease.
Small-molecule inhibitors of this enzyme would therefore serve as tools for validating the role of GNAS in the biology of these cancers and may have potential therapeutic applications.
However, further investigations have to aim at validating its role in BNP pathogenesis.
However, the N39ID mutation completely abolished the ligase activity, validating its role in the peptide ligation.
Raffinose drastically decreased in content upon imbibition validating its role as transient C storage molecule as suggested earlier [ 37, 38].
