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This illustrates the importance of validating response criteria against survival outcomes and we propose that a craniocaudal length reduction of >50% after CRT should be considered as an appropriate definition of "true partial response" for both primary and recurrent rectal cancer.
One drawback to the use of this definition is that it is likely to have produced a conservative estimate of deliberate self harm amongst Irish adolescents due to the requirement of validating response to the initial DSH question by a detailed description.
Similar(58)
Homogeneity of steroid HRE is analyzed and a reliable training dataset is constructed through extensive searching for experimentally validated response elements from more than 150 literature sources.
Furthermore, there are no validated response criteria for myositis, although recent studies have started to define outcome measures for application in future therapeutic trials.
We focus on brain activation preceding behaviorally validated response set shifts; hence, we stratified trials into behaviorally correct and incorrect responses.
Recent studies have focused on the benefits of various strategies in which treatments were tailored to achieve low levels of disease activity, as assessed using validated response criteria.
Increasingly, oncologic radiologists are expected to provide objective assessment of change in masses, on serial studies, in order to validate response or resistance to new chemotherapeutic agents.
The inability to validate responses is compounded by the fact that fires and sprinkler activations are rare events that yielded small numbers in our final sample.
CASI is becoming a popular method through which to validate responses from face-to-face interviews, but is also itself being validated against biomarkers.
Follow-up questions and probes were used to validate responses during the interviews.
Future studies should seek to validate responses further using recorded information sources such as school records.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com