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Renal fibrosis was inversely correlated with intrarenal RASAL1 mRNA expression levels (Fig. 10A) and the degree of intrarenal RASAL1 promoter CpG island methylation correlated with the degree of renal fibrosis, irrespective of the underlying disease (Fig. 10B), validating previous studies (Tampe et al., 2014).
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This latter finding validates previous studies indicating a role for 5-HT in suppression of the task-negative network during goal-directed behavior.
Our findings validate previous studies using ILI.
These results validate previous studies [ 20, 21].
Thus, our study validates previous studies and extends the findings to Hispanic and African American ethnic groups.
These results validate previous studies that showed increase numbers of TUNEL positive hepatocytes in livers of aged Fisher 44 rats (Higami et al. 1997).
Our results validate previous studies and extend the findings to men and women, all three race/ethnic groups, and varying states of glucose tolerance, family history of diabetes, and adiposity.
To validate previous studies, we compared the methylation status of T cells from older and younger mice via an unbiased antibody-based flow cytometric method (Delaney et al., 2012).
This analysis validated previous studies and found RDW to be a promising independent short- and long-term prognostic marker in ICU patients, which significantly improved the SAPS for risk stratification of patients.
Overall, replication studies including larger sample sizes of patients monitoring symptoms and automatically generated objective smartphone data for prolonged periods of time are needed to validate previous study findings.
The methodologies in this paper are validated in the identification of specific stable pathway markers (see below) which differentiate cancer phenotypes and validate previous studies identifying the same pathways and their component genes as significantly linked to cancer.
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