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We also aim to advance the field by developing and validating outcome measurement tools and subsequently conducting experimental work to evaluate the real impact of our curriculum.
A recent Food and Drug Administration Public workshop on Clinical Trial Outcome Assessments emphasised the need to define the context of use for validating outcome assessments: interestingly, the impact on general life concepts presented included productivity, health status, HRQL as well as satisfaction with health.
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The published trials varied in the quality of the methods used, often had inadequate sample sizes and showed difficulty in validating outcomes.
Such research could build upon the existing literature by incorporating, adapting and validating outcomes and measures that have been well-studied in other disease contexts; and could seek to elucidate additional outcomes that are important to children and their families.
Validated outcome measures - This review has emphasised the applicability of validated outcome measures.
The study used validated outcome measures; self-completion questionnaires which included a range of validated instruments (below) were developed and piloted among colorectal cancer patients treated at Flinders Medical Centre.
Most studies used or adapted a manual (71%), and had validated outcome measures (92%).
OMERACT has a working group to try and develop and validate outcome measures for large vessel vasculitis, which provides an opportunity for interested researchers to be involved in this process.
Validated outcome measures used.
Validated outcome measures are essential in monitoring disease severity.
- Strength: Validated outcome measures were used and assessed systematically.
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CEO of Professional Science Editing for Scientists @ prosciediting.com