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However, these approaches are quite complicated and can achieve substantially lower genomic coverage, making these technologies more suitable for validating findings than for initial discovery [30].
Confirmation that the O1-Ag was present on the cell surface by FACS analysis demonstrated that the O1-Ag saccharides alone on the cell surface were unable to protect against lysis by complement, further validating findings that the capsule modulates C3 deposition [26].
However, standard measures could greatly simplify the task of combining studies and validating findings.
These issues should be addressed in future research, hopefully also validating findings through the comparison of different studies.
Finally, our work shows that intervention with TMS may be a particularly powerful approach for validating findings from independent structural analyses of the brain.
More frequently, in questions such as those that populate the diabetes journals, ours is the role of validating findings emerging from bench research.
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Such an approach favors the idea that sharable data will validate findings, will promote their reuse, and will stimulate collaborations.
Projects that have crowdsourced analyses of a data set to diverse teams suggest that this approach can work to validate findings and offer new insights.
Plasma cotinine concentration was used to validate findings with self-reported smoking status.
The CS-CN method was validated, replicated, and yielded both novel and previously validated findings related to risk factors and potential treatments of psychiatric disorders.
This study is currently being replicated to validate findings and integrate more recent treatments.
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