The purpose of this study was to validate the association and to test whether the serum 25(OH D-linked genetic variants were assOH D-linkedh the occurrence of hip fracture in Japanese RA patients.
Next, we validated the association of miR-1246 with mutp53 in cancer patients.
Larger prospective studies with rigorous methodology should be considered to validate the association between citrus fruits and esophageal cancer.
To further validate the association, they turned to an ongoing prospective, longitudinal study of 1,500 patients with chest pain, shortness of breath or abnormal stress-test results, conducted by Stanford in collaboration with Mount Sinai Medical Center in New York City.
However, further well-designed studies with larger sample size, more ethnic groups and more CDKAL1 variants are required to validate the association between CDKAL1 and gestational glycemic traits.
As our sample size was limited, large-scale, well-designed studies are necessary to validate the association between the COX-2 765G>C polymorphism and AD.
Finally, we validated the association of miR-564 targets with cell invasiveness using 58 cancer cell lines in NCI60 panel and 12 breast cancer cell lines from GSE40059 dataset where higher levels of target genes expression in combination in invasive cell lines compared to less invasive cell lines were observed (Fig. 4G,H).
We prospectively validated the association of local tumor stage and grade as a predictive factor for occult lymph node micrometastasis in patients with penile carcinoma and clinically negative lymph nodes.
We validated the association of tumor necrosis with pathological features and clinical outcomes in a large international cohort of patients with upper tract urothelial carcinoma treated with radical nephroureterectomy.
We could not validate the association between DILI and rs72631567, rs28521457, or rs116561224.
