Theoretical astrophysics is based on laws of physics that have been validated with great precision through controlled experiments.
These results obtained with a very rapid convergence of the iterative algorithm combined with a very competitive genetic optimizer are validated with high precision on a free solution.
The method was validated with accuracy, precision, recovery, and stability and can be used to determine the pharmacokinetics of carbinoxamine enantiomers in human plasma.
The calibration standards and quality control samples were within acceptance criteria and the assay method validated with repeatable precision and accuracy.
All systems were validated with respect to precision, with repeatability and reproducibility <5% RSD, confirmed by the Snedecor F-test.
The assay was validated with respect to precision, detection and quantitation limits, accuracy/specificity, linearity, and range.
The developed method was further validated with respect to robustness, precision, sensitivity and linearity.
Prior to the experimental run, the HPLC method was validated with respect to accuracy, precision, sensitivity and selectivity.
This method has been appropriately validated with respect to selectivity, precision, accuracy and linearity following standards of FDA Guidelines for Bioanalytical Method Validation (FDA Guidance Document 2001).
However, the RIA developed by D'Ercole et al. has not been validated with respect to linearity, precision or recovery and, to the best of our knowledge, no further studies measuring rabbit IGF-I with this assay have been published thereafter.
The assay was validated with the inter assay precision determined by calculating coefficient of variance (CV) of ten repeats of high and low quality control (QC) samples in different plates and on separate dates, while intra assay precision was determined by calculating the mean CV of 40 samples run in duplicates on a single ELISA plate.
