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However, to date it has not been validated to the same extent as other more established measures.
APACHE III and APACHE IV have subsequently been released, but have not been validated to the same extent as APACHE II for preoperative risk prediction.
Unfortunately, more useful markers involving a functional response to a challenge such as in vivo challenge tests and ex vivo cellular function assays are much less standardised, have not been validated to the same extent and results can generally not be compared very well between laboratories.
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For the REE validation, the analysis was repeated eight times making sure each data point was tested and validated to establish whether the same variables significantly contributed to the prediction of REE, and then the standard deviations of the residuals (the individual differences between predicted and measured values) were compared.
In order to improve specificity of the hybridization and to focus on a few numbers of functions of the genes (inflammation, muscle metabolism), an equine oligonucleotide microarray database was designed and validated according to the same methods as previously described [ 24, 31].
We feel so blessed and humbled and also validated at the same time.
Owing to MapReduce and HDFS technique, the parallelized BPNNs with thirteen types of features dimension for every single generator are trained and validated at the same time.
These assays were developed and validated, to be run simultaneously with the same PCR program, according a harmonized standard procedure described in Barbau-Piednoir et al. (2013).
However experiments need to be done to validate the same.
For academia the challenges are different and revolve around lack of funding; the proportions between spending to test a new concept in experimental settings are logarithmically less than those spent to validate the same further in the clinics.
Also, the specificity of miRNA for asthma needs to be validated as the same miRNA might be differentially regulated in different lung diseases.
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