The method used to measure metabolic rate has been previously described and validated to confirm that values represent actual mammary tissue metabolism (Bauman et al., 1970; Bauman et al., 1973; Plaut et al., 1999b; Plaut et al., 2003).
The novel contributions of this paper are threefold: (1) describe and validate a method to represent arbitrary parametric surfaces implicitly; (2) represent arbitrary solids implicitly, including sharp features using level sets and boolean operations; (3) impose arbitrary Dirichlet and Neumann boundary conditions on the resulting implicitly defined boundaries.
Gene expression analysis also should be validated using internal controls to represent consistent mRNA expression levels, regardless of bacterial growth conditions [24].
We do not rely on the 10/18 genes that we validated below our cutoff to represent the sum of false negatives (there may be more), hence we cannot compute the true positive rate.
Although characterized as an NIP III member, the silicic acid transport ability of HbNIP2 1 needs to be experimentally validated since it seems to represent novel SDPs (S-F-V-H-G-N-R-T-Q in contrast to typical C/S-F/Y-A/E/L-H/R/Y-G-K/N/T-R-E/S/T-A/K/P/T) similar to that of GmNIP2 1 and GmNIP2 2 (S-Y-E-R-G-N-R-T-P) [ 53].
Failure to reject the null hypothesis therefore statistically validates the fitted model to represent the same population as that of the recorded values.
The mathematical principles and equations on which the simulator is based have been detailed in previous studies [20 22], which have also validated the simulator's ability to represent the pulmonary disease states of individual patients with chronic obstructive pulmonary disease and ARDS.
However, hsCRP is one of the most studied and best validated markers and is thought to represent overall LGI.
The methodology uses many of the internals of the CGAL library5 to represent and validate the 3D primitives, and uses existing methods to validate the 2D primitives.
