Pilot testing of the questionnaire was done and the final version was validated on eligible participants to determine whether it was acceptable, simple and readily understood.
Our dosing model should now be validated and prospectively evaluated to determine whether it will aid effective and safe warfarin therapy in children.
To validate this hypothesis and to determine whether it could be extended to all carbonylatable sites, we investigated the location of all CS within the peptides identified by LC nano-ESI MS/MS.
- Discriminative ability, as measured using ROC curve analysis, was better with the ANN. - Further research is required to validate the model and to determine whether there are practical or clinical advantages to one approach over the other.
Further prospective studies are, however, needed to validate the findings and to determine whether sVEGFR-3 can be a relevant biomarker in other sunitinib indications, such as renal cell carcinoma, and in treatments with other tyrosine kinase inhibitors.
To validate the method and to determine whether F-FDG uptake was correlated with histopathological changes in arthritis, we performed correlation analysis of individual quantitative PET results with semiquantitative clinical and histopathological scoring data.
To further validate these observations we wished to determine whether there was specificity among sirtuin (SIRT) lysine deacetylase family members in their capacity to regulate both Foxp3 acteylation and ubiquitination.
They validate and analyze the data to determine whether safety signals exist, and if warranted, develop an action plan to mitigate the identified risk.
Articles were read independently by two researchers who worked in close collaboration, checking and validating each other's coding to determine whether they met two inclusion criteria: that they were predominantly negative in tone and identified the gender of individuals focused on within the article.
In order to further validate our observations and to determine whether our proliferation meta-gene was simply identifying the Luminal B subtype of tumors, previously described as having high proliferation and poor outcome [ 4], we applied the proliferation meta-gene to a large microarray dataset containing 337 patients with long-term follow-up and containing a Luminal B group.
