Sentence examples for validated the function of from inspiring English sources

We validated the function of our model by measuring the accuracy of the model for the prediction of gene knockout essentiality.

We further validated the function of miR-23b-3p in MDR in a xenograft tumor model and clinical GC specimens, showing that this miRNA also regulated drug resistance in vivo.

Bi et al. [ 24] developed a growth system for rice by limiting N and identified N-responsive genes, validated the function of an early nodulin gene, OsENOD93-1, by over-expressing in rice.

Taken together, microarray analysis validated the function of endothelial S1004A in angiogenesis.> Using B16BL6 tumor tissues little expressing S100A4, we stained tumor microvessels for CD31 and S100A4 and found that there are subpopulations of endothelial cells in tumors, S100A4-positive anegativetive ones.

57 In another work, Yang et al integrated gene expression with gene copy number alternation, DNA methylation, associated miRNA expression, and miRNA target prediction to identify key regulatory miRNA genes that regulate ovarian cancer development and then experimentally validated the function of one predicted miRNA gene.

In addition to the loss-of-function assay, we also validated the functions of notch1a and notch3 through a gain-of-function approach.

RNAi analysis further validated the functions of HvZIP3 and HvZIP8 related to low grain Cd accumulation.

Finally, we have validated the function for handling the weighted values of the input nodes.

Following their application, functional genomic analyses are necessary to validate the function of any candidate sequences or alleles identified by the phylogenetic footprinting and shadowing methods; but even by themselves, both methods can provide valuable insights into the location of potential cis-regulatory sequences and the transcription factors that bind them.

Some functional genomics approaches like qRT-PCR may validate the function of these genes (Hu et al. 2009).

These results confirmed the functional incompatibility types of the S-haplotypes previously identified as S01−S08 and validate the function of four other putative S-haplotypes S09 (A06/ A07; Figure S9), S10 (B05; Figure S10), S12 (B17/ B18; Figure S12) and S13 (A04; Figure S13), but not S11 (B09/ B12; Figure S11).