Sentence examples for validated the binding of from inspiring English sources

We found that REF6 bind to the HSFA2 region in vitro (Fig. 4b), and validated the binding of REF6 in vivo by ChIP-qPCR (Fig. 4c).

We also validated the binding of OCT4 to an evolutionary conserved OCT4 motif, which we found in the proximal promoter region of the USP44 gene.

We validated the binding of OCT4 to the OCT4-SOX2 motif within the proximal promoter of the NANOG gene in NCCIT cells using a bandshift assay (Fig. 4).

These results validated the binding of miR-185 to the 3′-UTR of ATR mRNA.

We next cloned human and Tupaia NTCPs and validated the binding of the exogenously expressed NTCPs with the WTb peptide and an N-terminal myristoylated pre-S1 peptide with native residues.

Namely, functional studies have validated the binding of both miR-125b and miR-181a to the 3′-untranslated regions of PDRM1 and IRF4, with other predicted gene targets including IL6R, PAX5 and DUSP5 (Table 2).

To validate the binding of NLX to FLNA, we assessed binding of [3H]NLX to membranes prepared from the human melanoma cell line M2 that lacks filamin and to membranes from its FLNA-transfected subclone A7.

Protein complex immunoprecipitation (Co-IP) further validates the binding of Lxn and Rps3.

They validate the binding of the peptides by NMR, followed up by assays for fibril formation, and also show that the small molecules alleviate the toxicity of the amylogenic peptides to mammalian cells.

These data provide further worth of our BAP-24 probe because it can be used to validate the binding of small molecules to the α- or β-exosite of BoNT/A protease.

These laborious, costly procedures are required for even a simple task such as validating the binding of SH2 domains to a few candidate proteins (e.g., EGFR, ErbB2, etc).