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To calculate QALYs a preference based utility measure is needed; however, currently there are few validated preference based utility measures for children.
EQ-5D [ 51]: A widely used, validated, preference based generic HRQL instrument.
Quality of life and health status (6 weeks and 6 months): EQ-5D [ 51 ]: A widely used, validated, preference based generic HRQL instrument.
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No study used a validated preference-based QOL instrument such as the EQ-5D, HUI, or QWB.
Two groups have independently developed equations to map the MSWS-12 onto the Euroqol 5-Dimension (EQ-5D) [ 6], a validated, generic, preference-based health status measure.
The EQ-5D is a validated, generic preference-based measure of health status that comprises a 5-question multi-attribute questionnaire [ 6].
Utility values are typically sourced either from a clinical study or from the published literature, using a validated generic preference-based multiattribute utility instrument, such as EuroQol (EQ -5D.
Quality of life was measured using the validated, generic, preference-based EuroQoL Group 5 Dimension [EQ-5D] self-report questionnaire [ 23], which has been applied to a wide range of health conditions.
The SNPs were selected from dbSNP based on availability and their informativeness as of at the time the study was begun (information regarding tagging properties were limited at the time of SNP selection), with a preference for validated markers with a minor allele frequency (MAF) of >0.2.
DESIGN: OHNS physicians used an online version of a validated tool for assessing preferences for health plans in the setting of limited resources.
The total profile is valued with validated tariffs, resulting in preference-based utility scores that can be used in economic evaluations – the UK tariff was used in this study [12].
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